Carroll, David E.

Marr I

Huang GKL

Holt DC

Tong SYC

Boutlis CS

2017-07-21

Prostatic abscess is a rare complication of acute bacterial prostatitis and is most commonly caused by Enterobacteriaceae. We report on a case of prostatic abscess caused by Staphylococcus aureus and conduct a review of the literature. We present a case of S. aureus prostatic abscess that was successfully treated with a combination of antibiotic and surgical therapy. The isolate was non–multidrug-resistant, methicillin-resistant Staphylococcus aureus and was genotyped as clonal complex 5, an emerging regional clone that is trimethoprim resistant and Panton-Valentine leukocidin positive. This current case report is the first to describe the use of clindamycin step-down therapy. A literature review identified a further 39 cases of S. aureus prostatic abscesses, of which 26 were methicillin resistant. S. aureus is an uncommon cause of prostatic abscess. Optimal management includes both antibiotic therapy and surgical drainage. Our use of clindamycin as step-down therapy was guided by its excellent prostatic penetration.

BMC Infect Dis . 2017 Jul 21;17(1):509. doi: 10.1186/s12879-017-2605-4.

https://pubmed.ncbi.nlm.nih.gov/28732492/?otool=iaurydwlib

https://hdl.handle.net/10137/5214

MRSA

MSSA

PVL

Prostatic abscess

Prostatic abscesses

ST5-MRSA

Staphylococcus aureus

nmMRSA

Abscess

Anti-Bacterial Agents

Bacterial Toxins

Clindamycin

DNA, Bacterial

Humans

Male

Methicillin-Resistant Staphylococcus aureus

Prostatic Diseases

Staphylococcal Infections

Staphylococcus aureus

Tomography, X-Ray Computed

Staphylococcus aureus Prostatic abscess: a clinical case report and a review of the literature.

Journal Article

Publication