| Title |
|
HTLV-1c associated bronchiolitis in an Aboriginal man from Central Australia. |
|
|
| Publication Date |
|
| Author(s) |
|
| Affiliation |
|
Department of Medicine, Alice Springs Hospital, NT, Australia. |
|
|
Royal Adelaide Hospital, SA, Australia. |
|
|
University of Adelaide, SA, Australia. |
|
|
National Serology Reference Laboratory, Melbourne, Australia. |
|
|
Department of Medicine, Alice Springs Hospital, NT, Australia. |
|
|
Baker Heart and Diabetes Institute Central Australia, Alice Springs, NT, Australia. |
|
|
| Subject |
|
ASH, Alice Springs Hospital |
|
|
ATL, Adult T cell leukemia-lymphoma |
|
|
CTPA, Computed tomography pulmonary angiography |
|
|
HAB, HTLV associated bronchiolitis |
|
|
HTLV, Human T cell leukemia virus |
|
|
NIV, Non-invasive ventilation |
|
|
| Type of document |
|
| Entity Type |
|
| Abstract |
|
We describe the first case of HTLV associated bronchiolitis to be associated with HTLV-1c subtype infection. An Aboriginal man with HTLV-1 infection was repeatedly admitted to Alice Springs Hospital, central Australia, with hypercapnic respiratory failure from the age of 28 years. High resolution CT chest findings were consistent with bronchiolitis and large numbers of lymphocytes were found in bronchoalveolar lavage fluid (BALF). After extensive investigations failed to find a cause, he was tested for HTLV-1 and found to have a high HTLV-1c proviral load (6.8 %) in peripheral blood leukocytes and in BALF (4.7 %). The administration of systemic corticosteroids resulted in a rapid clinical response; however, he did not continue treatment after discharge and died due to respiratory failure in the community. |
|
|
| Link |
|
| Citation |
|
IDCases . 2020 Feb 11:19:e00714. doi: 10.1016/j.idcr.2020.e00714. eCollection 2020. |
|
|
| ISSN |
|
| Pubmed ID |
|
https://pubmed.ncbi.nlm.nih.gov/32123663/?otool=iaurydwlib |
|
|
