Douglas MW; Lum G; Roy J; Fisher DA; Anstey NM; Currie BJ

Author(s)

Douglas MW

Lum G

Roy J

Fisher DA

Anstey NM

Currie BJ

Publication Date

2004-07

Abstract

To define the relative incidence of organisms causing blood stream infections in a tropical setting with a very low prevalence of human immunodeficiency virus infection (<1%). A 12-month prospective study of blood stream infections in 2000 at Royal Darwin Hospital in the tropical north of Australia. Significant isolates were grown from 257 sets of blood cultures. Staphylococcus aureus was the most common isolate overall (28%); 26% of these were methicillin-resistant (MRSA). Escherichia coli was the most common cause of community-acquired bacteraemia. Burkholderia pseudomallei caused 32% of community acquired, bacteraemic pneumonia; 6% of bacteraemias overall. Vancomycin-resistant enterococci were not isolated. Crude mortality rates (13% overall; 9% attributable mortality) were lower than in most comparable studies. The major difference between these findings and surveys performed elsewhere is the presence of B. pseudomallei as a significant cause of bacteraemic community-acquired pneumonia. Our results demonstrate the effects of local environmental and patient characteristics on the range of organisms causing blood stream infections, and emphasize the important role of local microbiology laboratories in guiding empiric antibiotic therapy.

Affiliation

Department of Infectious Diseases, Royal Darwin Hospital, Casuarina, NT, Australia..

Citation

Tropical medicine & international health : TM & IH 2004-07; 9(7): 795-804

ISSN

1360-2276

Pubmed ID

https://pubmed.ncbi.nlm.nih.gov/15228489/?otool=iaurydwlib

Link

https://hdl.handle.net/10137/5831

MESH subject

Adolescent

Adult

Bacteremia

Child

Community-Acquired Infections

Cross Infection

Drug Resistance, Bacterial

Escherichia coli Infections

Female

Humans

Male

Melioidosis

Middle Aged

Northern Territory

Oceanic Ancestry Group

Prevalence

Prospective Studies

Risk Factors

Staphylococcal Infections

Title

Epidemiology of community-acquired and nosocomial bloodstream infections in tropical Australia: a 12-month prospective study.

Type of document

Journal Article

Entity Type

Publication

Author(s)	Douglas MW Lum G Roy J Fisher DA Anstey NM Currie BJ
Publication Date	2004-07
Abstract	To define the relative incidence of organisms causing blood stream infections in a tropical setting with a very low prevalence of human immunodeficiency virus infection (<1%). A 12-month prospective study of blood stream infections in 2000 at Royal Darwin Hospital in the tropical north of Australia. Significant isolates were grown from 257 sets of blood cultures. Staphylococcus aureus was the most common isolate overall (28%); 26% of these were methicillin-resistant (MRSA). Escherichia coli was the most common cause of community-acquired bacteraemia. Burkholderia pseudomallei caused 32% of community acquired, bacteraemic pneumonia; 6% of bacteraemias overall. Vancomycin-resistant enterococci were not isolated. Crude mortality rates (13% overall; 9% attributable mortality) were lower than in most comparable studies. The major difference between these findings and surveys performed elsewhere is the presence of B. pseudomallei as a significant cause of bacteraemic community-acquired pneumonia. Our results demonstrate the effects of local environmental and patient characteristics on the range of organisms causing blood stream infections, and emphasize the important role of local microbiology laboratories in guiding empiric antibiotic therapy.
Affiliation	Department of Infectious Diseases, Royal Darwin Hospital, Casuarina, NT, Australia..
Citation	Tropical medicine & international health : TM & IH 2004-07; 9(7): 795-804
ISSN	1360-2276
Pubmed ID	https://pubmed.ncbi.nlm.nih.gov/15228489/?otool=iaurydwlib
Link	https://hdl.handle.net/10137/5831
MESH subject	Adolescent Adult Bacteremia Child Community-Acquired Infections Cross Infection Drug Resistance, Bacterial Escherichia coli Infections Female Humans Male Melioidosis Middle Aged Northern Territory Oceanic Ancestry Group Prevalence Prospective Studies Risk Factors Staphylococcal Infections
Title	Epidemiology of community-acquired and nosocomial bloodstream infections in tropical Australia: a 12-month prospective study.
Type of document	Journal Article
Entity Type	Publication

Epidemiology of community-acquired and nosocomial bloodstream infections in tropical Australia: a 12-month prospective study.

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