Lower Rates of Bloodstream Infection in Patients on Hemodialysis Receiving Trimethoprim-Sulfamethoxazole Melioidosis Prophylaxis.

Author(s)
Bryce, Aliya
Davison, Sara
Currie, Bart
Birrell, Johanna
Baird, Robert
Abeyaratne, Asanga
Majoni, Sandawana William
Brewster-O'Brien, Teana
Tong, Steven Y C
Publication Date
2024-07-31
Abstract
Hemodialysis is a risk factor for bloodstream infection (SAB). In this single-center study, SAB rates were 56% lower during the monsoonal wet season when patients on hemodialysis receive supervised melioidosis prophylaxis with trimethoprim-sulfamethoxazole. This intervention may reduce SAB rates in high-risk patients; however, further targeted studies are required.
Affiliation
Department of Infectious Diseases, Royal Darwin Hospital, Darwin, Northern Territory, Australia.
Department of General Medicine, Royal Melbourne Hospital, Melbourne, Victoria, Australia.
Department of Infectious Diseases, Royal Darwin Hospital, Darwin, Northern Territory, Australia.
Department of Infectious Diseases, Royal Darwin Hospital, Darwin, Northern Territory, Australia.
Menzies School of Health Research, Charles Darwin University, Darwin, Northern Territory, Australia.
Northern Territory Centre for Disease Control, NT Health, Darwin, Northern Territory, Australia.
Department of Infectious Diseases, Royal Darwin Hospital, Darwin, Northern Territory, Australia.
Menzies School of Health Research, Charles Darwin University, Darwin, Northern Territory, Australia.
Department of Nephrology, Royal Darwin Hospital, Darwin, Northern Territory, Australia.
Flinders University and Northern Territory Medical Program, Royal Darwin Hospital Campus, Darwin, Northern Territory, Australia.
Menzies School of Health Research, Charles Darwin University, Darwin, Northern Territory, Australia.
Department of Nephrology, Royal Darwin Hospital, Darwin, Northern Territory, Australia.
Flinders University and Northern Territory Medical Program, Royal Darwin Hospital Campus, Darwin, Northern Territory, Australia.
Department of Nephrology, Royal Darwin Hospital, Darwin, Northern Territory, Australia.
Victorian Infectious Diseases Service, The Royal Melbourne Hospital at the Peter Doherty Institute for Infection and Immunity, Melbourne, Victoria, Australia.
Department of Infectious Diseases, The University of Melbourne at the Peter Doherty Institute for Infection and Immunity, Melbourne, Victoria, Australia.
Citation
Open Forum Infect Dis . 2024 Jul 31;11(8):ofae431. doi: 10.1093/ofid/ofae431. eCollection 2024 Aug.
ISSN
2328-8957
OrcId
0000-0002-2006-5122
0000-0002-8878-8837
0000-0001-9593-1868
Pubmed ID
https://pubmed.ncbi.nlm.nih.gov/39130084/?otool=iaurydwlib
Link
Subject
Staphylococcus aureus
antibiotic prophylaxis
bloodstream infection
hemodialysis
trimethoprim-sulfamethoxazole
MESH subject
Title
Lower Rates of Bloodstream Infection in Patients on Hemodialysis Receiving Trimethoprim-Sulfamethoxazole Melioidosis Prophylaxis.
Type of document
Journal Article
Entity Type
Publication

Files:

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