Trough concentrations of vancomycin: adult therapeutic targets are not appropriate for children.

Author(s)
Gordon, Claire L
Thompson, Chantelle
Carapetis, Jonathan R
Turnidge, John
Kilburn, Charles
Currie, Bart
Publication Date
2012-12-01
Abstract
Despite the need for effective vancomycin therapy, there are few data guiding vancomycin monitoring in children. We reviewed retrospectively vancomycin use in children 1 month to 12 years of age. Initial and adjusted target trough vancomycin concentrations in serum were infrequently achieved regardless of the dosing schedule. Currently recommended trough concentrations need to be re-examined with a more detailed pharmacokinetic study in children.
Citation
The Pediatric infectious disease journal 2012-12; 31(12): 1269-71
Pubmed ID
https://pubmed.ncbi.nlm.nih.gov/22828642/?otool=iaurydwlib
Link
MESH subject
Anti-Bacterial Agents
Child
Child, Preschool
Female
Humans
Infant
Male
Serum
Vancomycin
Title
Trough concentrations of vancomycin: adult therapeutic targets are not appropriate for children.
Type of document
Journal Article
Entity Type
Publication

Files:

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