Holwell, Anna

Sajiv, Cherian

Barzil F

Brady, Stephen

Hughes Wagadagam , Jaquelyne

2017-03-01

The Northern Territory has the highest Australian incidence rate per population of haemodialysis (HD)-dependent chronic kidney disease (CKD). Our aim was to describe the average annual estimated glomerular filtration rate (eGFR) decline in the previous five years for adults commencing HD in Central Australia in 2012. No patients were started on peritoneal dialysis in Central Australia in this period. Central Australian clinical databases were retrospectively audited for serum creatinine (sCR), albuminuria (ACR), glycated Hb (HbA1c), and eGFR for the five years preceding HD-start. All results were included for the audit duration (from the earliest date for five years (audit entry, AE) prior to HD-start); an average annual eGFR decline was calculated using the CKD epidemiology collaborative (CKD-EPI) equation. Forty-nine clients initiated HD in 2012 (96% Indigenous, 65% female, age 45 years, diabetes primary renal disease 80%). The median (IQR) audit duration was 3.8 (2.5, 4.6) years. At audit-entry, the mean ACR and eGFR were 157 mg/mmol and 51 ml/min/1.73m2 respectively, corresponding to 91% clients having macroalbuminuria (ACR >30 mg/mmol), and 15% having an eGFR

(Holwell, A.) Consultant General Physician, Alice Springs Hospital, Alice Springs, NT, Australia, email: anna.holwell@nt.gov.au, tel: +61 (0) 8 8951 7777

(Sajiv, C.) Sr Staff Specialist and Head, Central Australian Renal Services; and Director, NT Renal Services, Alice Springs Hospital/Royal Darwin Hospital, NT; and Senior Lecturer, Flinders University, SA, Australia

(Brady, S.) Consultant General Physician, Alice Springs Hospital, Alice Springs, NT, Australia

(Hughes, J.T.) NHMRC Early Career Research Fellow, The Menzies School of HealthResearch, Charles Darwin University and Consultant Nephrologist, Royal Darwin Hospital, NT, Australia

Holwell, A., Sajiv, C., Barzi, F., Brady, S., & Hughes, J. T. (2017). Rapid progression of chronic kidney disease in five years prior to haemodialysis initiation in Central Australia. Renal Society of Australasia Journal, 13(1), 5–8.

1832-3804

https://hdl.handle.net/10137/12052

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Chronic renal failure

Treatment

Glomerular filtration rate

Acute renal failure

Kidneys

Diseases

Diagnosis

Social medicine

Haemodialysis

Patients

Northern Territory

Rapid progression of chronic kidney disease in five years prior to haemodialysis initiation in Central Australia

Journal Article

Publication