Endometrial cancer recurrence presenting as anterior abdominal wall necrotising fasciitis.

Author(s)
Barrow, Indira Josephine
Paredes, Steven Ronald
Siwicki, Kasia
Reddipogu, Jonathan
Publication Date
2025-04-02
Abstract
Endometrial cancer is the second leading cause of malignancy in women worldwide. Risk of recurrence and treatment depends on tumour grade, stage and more recently, molecular classification. This case details an atypical presentation of endometrial cancer recurrence. A postmenopausal woman presented to hospital in septic shock with anterior abdominal wall necrotising fasciitis. She was 5 years into her surveillance for FIGO (International Federation of Gynaecology and Obstetrics) Grade III, Stage IIIA mixed endometrioid and clear cell endometrial adenocarcinoma, treated by total abdominal hysterectomy, bilateral salpingo-oophorectomy, vaginal brachytherapy, radiotherapy and chemotherapy. Necrotising fasciitis was localised to a fluid collection associated with biological mesh on the anterior abdominal wall. Histopathology and cytology of the fluid collection revealed high-grade serous endometrial carcinoma. Recurrence in the incision has previously been described in the literature, however not as a fluid collection in association with biological mesh nor causing necrotising fasciitis of the anterior abdominal wall.
Affiliation
Obstetrics and Gynaecology, Alice Springs Hospital, Alice Springs, Northern Territory, Australia indirabarrow@outlook.com.
General Surgery, Alice Springs Hospital, Alice Springs, Northern Territory, Australia.
Obstetrics and Gynaecology, Alice Springs Hospital, Alice Springs, Northern Territory, Australia.
General Surgery, Alice Springs Hospital, Alice Springs, Northern Territory, Australia.
Citation
BMJ Case Rep . 2025 Apr 2;18(4):e263718. doi: 10.1136/bcr-2024-263718.
ISSN
1757-790X
OrcId
0009-0002-2355-9416
Pubmed ID
https://pubmed.ncbi.nlm.nih.gov/40180345/?otool=iaurydwlib
Link
Subject
General surgery
Gynecological cancer
MESH subject
Humans
Female
Fasciitis, Necrotizing
Abdominal Wall
Endometrial Neoplasms
Neoplasm Recurrence, Local
Middle Aged
Hysterectomy
Diagnosis, Differential
Title
Endometrial cancer recurrence presenting as anterior abdominal wall necrotising fasciitis.
Type of document
Journal Article
Entity Type
Publication

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