| Author(s) |
Nixon, Joanne
Hennessy, Jann
Baird, Robert
|
| Publication Date |
2024-07-01
|
| Abstract |
This retrospective study reviewed the macrolide resistance rates of Group A Streptococcus (GAS) isolates in the Northern Territory from 2012 to 2023. Clindamycin and erythromycin resistance rates peaked in 2021, at 6.0% and 12.2% respectively, and then returned to near baseline at 1-2% in 2023. Increased resistance rates were identified in the Top End of Australia from mid-2020, followed 15 months later by high rates in central Australia in 2022. Factors associated with resistant isolates were living in a rural region and of age 18 years and older. Possible explanations include a transient clonal introduction of a resistant GAS strain to the Northern Territory from 2020 to 2022. Ongoing surveillance is required to monitor regional trends and identify temporal variations in resistant isolates.
|
| Affiliation |
Advanced Trainee Infectious Diseases and Acute and General Care Medicine.
Territory Pathology, Royal Darwin Hospital, Rocklands Drive TIWI NT 0810 Australia.
Department of Microbiology, Royal Darwin Hospital, Rocklands Drive TIWI NT 0810 Australia.
Territory Pathology, Royal Darwin Hospital, Rocklands Drive TIWI NT 0810 Australia.
Department of Microbiology, Royal Darwin Hospital, Rocklands Drive TIWI NT 0810 Australia.
Territory Pathology, Royal Darwin Hospital, Rocklands Drive TIWI NT 0810 Australia.
Clinical Microbiologist and Director of Pathology, Territory Pathology, Royal Darwin Hospital, Rocklands Drive TIWI NT 0810 Australia.
|
| Citation |
Commun Dis Intell (2018) . 2024 Jul 17:48. doi: 10.33321/cdi.2024.48.31.
|
| ISSN |
2209-6051
|
| OrcId | |
| Pubmed ID |
https://pubmed.ncbi.nlm.nih.gov/39021124/?otool=iaurydwlib
|
| Link | |
| Subject |
Group A streptococcus
Northern Territory
Streptococcus pyogenes
clindamycin
erythromycin
resistance
|
| MESH subject |
Clindamycin
Humans
Erythromycin
Northern Territory
Streptococcus pyogenes
Anti-Bacterial Agents
Streptococcal Infections
Retrospective Studies
Female
Adult
Male
Drug Resistance, Bacterial
Adolescent
Middle Aged
Child
Young Adult
Child, Preschool
Aged
Microbial Sensitivity Tests
Infant
|
| Title |
Tracking trends in the Top End: clindamycin and erythromycin resistance in Group A Streptococcus in the Northern Territory, 2012-2023.
|
| Type of document |
Journal Article
|
| Entity Type |
Publication
|
| Name | Size | format | Description | Link |
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