Cook, Heather M

Giele, Caroline M

Jayasinghe, Sanjay H

Wakefield, Angela

Krause, Vicki L

2020-09-15

Between 2010 and 2013, an outbreak of serotype-1 sequence type 306 (ST306) invasive pneumococcal disease (IPD) occurred primarily in remote locations of Northern and Central Australia. This is a descriptive study of the epidemiology of the outbreak using nationwide IPD surveillance data, supplemented with more detailed data held by affected jurisdictions, and of the response to the outbreak, including vaccination strategies. In the year the outbreak peaked (2011), serotype-1 IPD incidence was over 30-fold higher in the affected regions than in the rest of Australia (incidence rate ratio: 30.7 [95% CI 20.1-48.9]). The study includes 245 cases of serotype-1 IPD from the outbreak regions, with 75.5% identified as Indigenous. No reported cases of serotype-1 IPD occurred in young children who had completed either a 10- or 13-valent pneumococcal conjugate vaccine schedule. However serotype-1 IPD did occur in older children who had previously received 23-valent pneumococcal polysaccharide vaccine. Development of public-health-focused national IPD management guidelines, including suitable vaccine strategies for consistent use nationwide, could potentially decrease the duration and intensity of similar outbreaks in the future.

Enhanced Invasive Pneumococcal Disease Surveillance Working Group; Centre for Disease Control, Top End Health Services, Northern Territory, Australia.

Enhanced Invasive Pneumococcal Disease Surveillance Working Group; Communicable Diseases Control, Health Department of Western Australia, Australia.

Enhanced Invasive Pneumococcal Disease Surveillance Working Group; National Centre for Immunisation Research and Surveillance (NCIRS); Discipline of Child and Adolescent Health, Faculty of Medicine and Health, University of Sydney, Australia.

Enhanced Invasive Pneumococcal Disease Surveillance Working Group; Communicable Diseases Branch, Queensland Health, Australia.

© Commonwealth of Australia CC BY-NC-ND.

Commun Dis Intell (2018). 2020 Sep 15;44. doi: 10.33321/cdi.2020.44.66.

https://pubmed.ncbi.nlm.nih.gov/32988336/?otool=iaurydwlib

https://hdl.handle.net/10137/11807

44

Adolescent

Adult

Aged

Aged, 80 and over

Australia

Child

Child, Preschool

*Disease Outbreaks

Humans

*Indigenous Peoples

Infant

Middle Aged

Oceanic Ancestry Group

Pneumococcal Infections/*epidemiology/*microbiology/prevention & control

Pneumococcal Vaccines/immunology

Serotyping

Streptococcus pneumoniae/*classification

Vaccination

Young Adult

An outbreak of serotype-1 sequence type 306 invasive pneumococcal disease in an Australian Indigenous population.

Journal Article

Publication