Whole-Genome Sequences of Burkholderia pseudomallei Isolates Exhibiting Decreased Meropenem Susceptibility.

Author(s)
Price EP
Smith ML
Paxinos EE
Tallon LJ
Sadzewicz L
Sengamalay N
Baird, Robert
Currie, Bart
Sarovich DS
Publication Date
2017-04-06
Abstract
We report here paired isogenic Burkholderia pseudomallei genomes obtained from three patients receiving intravenous meropenem for melioidosis treatment, with post-meropenem isolates developing decreased susceptibility. Two genomes were finished, and four were drafted to improved high-quality standard. These genomes will be used to identify meropenem resistance mechanisms in B. pseudomallei.
Affiliation
Global and Tropical Health Division, Menzies School of Health Research, Charles Darwin University, Darwin, Northern Territory, Australia eprice@usc.edu.au.. Centre for Animal Health Innovation, Faculty of Science, Health, Education and Engineering, University of the Sunshine Coast, Sippy Downs, Queensland, Australia..
Pacific Biosciences, Menlo Park, California, USA..
Pacific Biosciences, Menlo Park, California, USA..
Institute for Genome Sciences, University of Maryland School of Medicine, Baltimore, Maryland, USA..
Institute for Genome Sciences, University of Maryland School of Medicine, Baltimore, Maryland, USA..
Institute for Genome Sciences, University of Maryland School of Medicine, Baltimore, Maryland, USA..
Department of Infectious Diseases and Northern Territory Medical Program, Royal Darwin Hospital, Darwin, Northern Territory, Australia.. Pathology Department, Royal Darwin Hospital, Darwin, Northern Territory, Australia..
Global and Tropical Health Division, Menzies School of Health Research, Charles Darwin University, Darwin, Northern Territory, Australia.. Department of Infectious Diseases and Northern Territory Medical Program, Royal Darwin Hospital, Darwin, Northern Territory, Australia..
Global and Tropical Health Division, Menzies School of Health Research, Charles Darwin University, Darwin, Northern Territory, Australia.. Centre for Animal Health Innovation, Faculty of Science, Health, Education and Engineering, University of the Sunshine Coast, Sippy Downs, Queensland, Australia..
Citation
Genome Announc . 2017 Apr 6;5(14):e00053-17. doi: 10.1128/genomeA.00053-17.
ISSN
2169-8287
OrcId
0000-0002-1079-4882
0000-0002-6944-3980
Pubmed ID
https://pubmed.ncbi.nlm.nih.gov/28385830/?otool=iaurydwlib
Link
Title
Whole-Genome Sequences of Burkholderia pseudomallei Isolates Exhibiting Decreased Meropenem Susceptibility.
Type of document
Journal Article
Entity Type
Publication

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