Northern Territory perspectives on heart failure with comorbidities – understanding trial validity and exploring collaborative opportunities to broaden the evidence base.

Author(s)
Thomas, Merlin C
Publication Date
2015-06-01
Abstract
Congestive Heart Failure (CHF) is an ambulatory care sensitive condition, associated with significant morbidity and mortality, rarely with cure. Outpatient based pharmacological management represents the main and most important aspect of care, and is usually lifelong. This narrative styled opinion review looks at the pharmacological agents recommended in the guidelines in context of the Northern Territory (NT) of Australia. We explore the concept of validity, a term used to describe the basis of standardising a particular trial or study and the population to which it is applicable. We aim to highlight the problems of the current guidelines based approach. We also present alternatives that could utilise the core principles from major trials, while incorporating regional considerations, which could benefit clients living in the NT and remote Australia.
Citation
Heart Lung Circ . 2015 Jun;24(6):536-43. doi: 10.1016/j.hlc.2014.12.007. Epub 2014 Dec 24.
Pubmed ID
https://pubmed.ncbi.nlm.nih.gov/25637942/?otool=iaurydwlib
Link
Subject
Guidelines
Heart Failure
Indigenous Australians
Remote
Rural
Therapeutics
MESH subject
Australia
Cardiovascular Agents
Clinical Trials as Topic
Comorbidity
Evidence-Based Medicine
Female
Health Services, Indigenous
Heart Failure
Humans
Male
Northern Territory
Practice Guidelines as Topic
Remote Consultation
Reproducibility of Results
Outcome Assessment (Health Care)
Title
Northern Territory perspectives on heart failure with comorbidities – understanding trial validity and exploring collaborative opportunities to broaden the evidence base.
Type of document
Journal Article
Entity Type
Publication

Files:

NameSizeformatDescriptionLink
https://digitallibrary.health.nt.gov.au/nthealthserver/api/core/items/454fda4b-a531-4d92-80ff-b636e6dd9011