Pectoralis major radiation recall.

2019-03-01

Hack, Emma

Thachil, Thanuja

Karanth, Narayan

Department of Medicine, Royal Darwin Hospital, Tiwi, Northern Territory, Australia.

Department of Medicine, Royal Darwin Hospital, Tiwi, Northern Territory, Australia.

Department of Medicine, Royal Darwin Hospital, Tiwi, Northern Territory, Australia.

adverse events

chest

clinical site

discipline

general

medical imaging

radiation oncology

Carcinoma, Non-Small-Cell Lung

Deoxycytidine

Humans

Lung Neoplasms

Male

Middle Aged

Pectoralis Muscles

Radiation Injuries

Gemcitabine

Journal Article

Publication

0000-0001-6461-2901

Radiation recall is an uncommon phenomenon describing an acute localised inflammatory toxicity affecting tissue previously exposed to radiotherapy. It is precipitated by administration of certain medications, including chemotherapy. We describe a case involving a 50-year-old Aboriginal male smoker from a remote community in Northern Australia who underwent treatment for stage IV non-small cell lung cancer with localised radiotherapy to the primary right upper lung lobe tumour. This was followed by a course of gemcitabine, which was ceased prematurely after four cycles when he presented with radiation recall to his right pectoralis major. Our case description is complemented with a brief review of current literature regarding our case and gemcitabine-related radiation recall. This was in the context of concurrent musculoskeletal strain, an as-yet unreported association with radiation recall. His condition settled with steroid administration and discontinuation of gemcitabine.

link

J Med Radiat Sci . 2019 Mar;66(1):62-65. doi: 10.1002/jmrs.303. Epub 2018 Sep 9.

2051-3909

https://pubmed.ncbi.nlm.nih.gov/30198200/?otool=iaurydwlib