Heraganahally, Subash

Howarth, Timothy

Gibbs, Claire

Heraganahally, Sanjana

Sorger, Lisa

2024-06-12

There is limited evidence in the literature illustrating chest computed tomography (CT) characteristics among adult Aboriginal Australians with bronchiectasis. This retrospective study evaluates the radiological characteristics of bronchiectasis in Aboriginal Australians residing in the Top End, Northern Territory of Australia.Patients aged >18 years with chest CT-confirmed bronchiectasis between 2011 and 2020 were included. Demographics and relevant clinical parameters were collected. Alongside confirming bronchiectasis, chest CT reports were assessed for (i) lobar location (ii) unilateral or bilateral involvement and (iii) bronchiectasis type when available.A total of 459 patients were identified with chest CT-confirmed bronchiectasis, with a median age of 47 years, and 55% were females. Bronchiectasis was predominantly recorded in the left lower lobe (LLL) (73%), followed by the right lower lobe (RLL) (62%) and the left upper lobe (LUL) was least common (22%). Females recorded the right middle lobe (RML) affected significantly more often than males (50 vs. 34%, P = 0.012). Bilateral involvement was common (74%), with the strongest pairwise correlation associated between the right upper lobe (RUL) and LUL (P < 0.001). Cylindrical (50%) and cystic (28%) types were most common. The RML and LLL showed positive correlation with cylindrical and LUL with cystic bronchiectasis. Neither lobar location nor bronchiectasis type showed any significant association with lung function parameters other than RML, Lingula and LUL involvement being associated with better percent predicted values of diffusing capacity for carbon monoxide. There were no significant associations between sputum culture and type or lobar locations of bronchiectasis except for non-Aspergillus fungus culture prevalence was higher with cystic or cylindrical types.The results of this study may be an avenue to develop CT bronchiectasis severity scale in the future specific for Aboriginal Australians.

Department of Respiratory and Sleep Medicine, Royal Darwin Hospital, Darwin, Northern Territory, Australia.

Flinders University, College of Medicine and Public Health, Darwin, Northern Territory, Australia.

Darwin Respiratory and Sleep Health, Darwin Private Hospital, Darwin, Northern Territory, Australia.

Darwin Respiratory and Sleep Health, Darwin Private Hospital, Darwin, Northern Territory, Australia.

Department of Technical Physics, University of Eastern Finland, Kuopio, North Savo, Finland.

Diagnostic Imaging Center, Kuopio University Hospital, Kuopio, North Savo, Finland.

Department of Respiratory and Sleep Medicine, Royal Darwin Hospital, Darwin, Northern Territory, Australia.

Flinders University, College of Medicine and Public Health, Darwin, Northern Territory, Australia.

School of Medicine and Dentistry, James Cook University, Townsville, Queensland, Australia.

Integral Diagnostics, Melbourne, Victoria, Australia.

Apex Radiology, Mandurah, Western Australia, Australia.

J Med Imaging Radiat Oncol . 2024 Jun 12. doi: 10.1111/1754-9485.13671. Online ahead of print.

1754-9485

0000-0003-0788-7137

0000-0003-3028-0376

0000-0003-4130-3668

0000-0001-5470-1118

https://pubmed.ncbi.nlm.nih.gov/38864251/?otool=iaurydwlib

https://hdl.handle.net/10137/13403

medical imaging

pulmonary

radiology

respiratory

x‐ray

Chest computed tomography findings among adult Aboriginal Australians with bronchiectasis in the Top End Northern Territory of Australia.

Journal Article

Publication