Carino, Marylin

Nguyen, Jonathan

New, Ru Hui

Kirkham, Renae

Maple-Brown, Louise

Mack, Shiree

MacKay, Diana

Titmuss, Angela

2025-03-10

There is a high prevalence of type 2 diabetes (T2D) in First Nations populations worldwide, increasingly at younger ages. This review aims to identify interventions for the prevention of T2D in First Nations children and young people aged 4-25 years.A systematic search of both published and unpublished literature until March 2024 was performed using 15 electronic databases, including MEDLINE, CINAHL, EMBASE, Scopus, Cochrane Library, ATSIHealth, OpenGrey and specific First Nations databases. Eligible studies included First Nations participants aged 4-25 years without T2D, exploring interventions to prevent T2D. Outcomes included knowledge of diabetes, anthropometry and physiology, diet and nutrition, physical activity, glycemic indicators and psychosocial indicators.Fourteen pre-post exposure non-controlled studies were included, evaluating nine programs. Programs were culturally adapted and primarily school-based, focusing on individual-level behaviour modification in nutrition and physical activity. Most studies assessing knowledge outcomes reported improvement. There were inconsistent findings regarding impacts on dietary intake and glycemia. One home-based program achieved improvements across a range of outcomes, including body mass index, physical activity and psychosocial scores.Despite the increasing prevalence of T2D in First Nations children and young people, evidence of effective preventive strategies within these populations remains limited.

Wellbeing and Preventable Chronic Diseases Division, Menzies School of Health Research, Charles Darwin University, Darwin, Northern Territory, Australia.

Department of Paediatrics, Division of Women, Children and Youth, Royal Darwin Hospital, Darwin, Northern Territory, Australia.

Department of Endocrinology, Royal Darwin Hospital, Darwin, Northern Territory, Australia.

Wellbeing and Preventable Chronic Diseases Division, Menzies School of Health Research, Charles Darwin University, Darwin, Northern Territory, Australia.

Wellbeing and Preventable Chronic Diseases Division, Menzies School of Health Research, Charles Darwin University, Darwin, Northern Territory, Australia.

Department of Endocrinology, Royal Darwin Hospital, Darwin, Northern Territory, Australia.

Wellbeing and Preventable Chronic Diseases Division, Menzies School of Health Research, Charles Darwin University, Darwin, Northern Territory, Australia.

Wellbeing and Preventable Chronic Diseases Division, Menzies School of Health Research, Charles Darwin University, Darwin, Northern Territory, Australia.

Department of Endocrinology, Royal Darwin Hospital, Darwin, Northern Territory, Australia.

Wellbeing and Preventable Chronic Diseases Division, Menzies School of Health Research, Charles Darwin University, Darwin, Northern Territory, Australia.

Department of Paediatrics, Division of Women, Children and Youth, Royal Darwin Hospital, Darwin, Northern Territory, Australia.

Pediatr Obes . 2025 Mar 10:e70009. doi: 10.1111/ijpo.70009. Online ahead of print.

2047-6310

0000-0001-8122-2075

0000-0002-8209-886X

0000-0002-9865-1252

https://pubmed.ncbi.nlm.nih.gov/40065629/?otool=iaurydwlib

https://hdl.handle.net/10137/14182

First Nations

children

paediatrics

systematic review

type 2 diabetes

A systematic review of prevention strategies for type 2 diabetes in First Nations children and young people.

Journal Article

Publication