Repository logo

Acronym
NAVIGATE
Project Title
A phase 2 Basket Study of the Oral TRK Inhibitor larotrectinib in subjects with NTRK Fusion – Positive Tumors
Principal Investigator
Butt, Sabeeh
Start Date
April 1, 2021
Investigators
Project Web Site
Keywords
Solid Tumors Harboring NTRK Fusion
Project Type
Interventional/Clinical trials research
Location
Region
Keywords

Solid Tumors Harborin...

Description
The Clinical Trial is investigating how well different types of cancer respond to the drug called Larotrectinib. The cancer must have a change in a particular gene (NTRK1, NTRK2 or NTRK3). Larotrectinbib is a drug that blocks the actions of these NTRK genes in cancer cells and can therefore be used to treat cancer. There are currently no other standard forms of treatment that would be able to cure or effectively treat the ccancer concisting of this gene

NT Health Library Services acknowledges the Traditional Custodians of Country throughout the Northern Territory and recognises their continuing cultural and spiritual connections to the lands, waters, and communities. We pay our respects to elders past, present and emerging, and extend that respect to all Aboriginal and Torres Strait Islander people across the Northern Territory and beyond, many of whom are represented in our collections.

© 2025 Northern Territory Government of Australia