All Publications
4121
Projects
61
People
142
Recent Additions
  • Publication
    Northern Territory Suicide Prevention Strategic Framework 2018-2023 - Implementation Plan
    (Department of Health, 2019-03-04)
    Mental Health Alcohol and Other Drugs Branch
    This Implementation Plan supports the Northern Territory Suicide Prevention Strategic Framework. Given that suicide is an issue that affects all our community, we are all responsible for its prevention. All groups and agencies across our community need to come together, with a coordinated and collaborative approach, making the best use of shared skills and resources. That includes health services, education, industry, housing, business, the legal and justice systems, emergency services, community based organisations, volunteer and sporting groups, the media, private sector and any other interested party.
  • Organizational Unit
  • Organizational Unit
  • Organizational Unit
    Medical Retrieval and Consultation Centre (MRaCC)
    Also known as the Central Australian Retrieval Service
  • Organizational Unit
    Psychiatry
Most viewed
  • Publication
    Medicines & Poisons Control Information sheet No. 320.4 : Medical Practitioner Guide to Suppling Isotretinoin
    (Department of Health, 2014)
    Department of Health
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    Isotretinoin
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    Department of Health
  • Publication
    Mortality in the Northern Territory 1981-2000 - part 1: Key indicators & overview
    (Health Gains Planning, DHCS, 2004-11) ;
    Guthridge, Steve
    This report is the first volume in the Mortality in the Northern Territory 1981-2000 series, and provides an overview of information on Northern Territory (NT) deaths for the years 1981 to 2000. It provides detailed statistics for deaths from all causes, and for each of the major International Classification of Disease (ICD) chapters. Age-adjusted death rate, age-specific death rate and life expectancy are used to describe and compare health status within the Northern Territory population. Australian data is provided for comparison, where appropriate. The two subsequent volumes of this series provide disease specific causes of death including analysis of associated and underlying causes of death.
  • Publication
    Sexual Assault Referral Centre Protocol
    (2000)
    Territory Health Services
    Sexual Assault Referral Centre protocol for Territory Health Services in 2000
  • Publication
    Petrol sniffer's encephalopathy.
    (1994-06-20)
    Currie BJ
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    Burrow J
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    Fisher D
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    Howard D
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    McElver M
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    Burns C
  • Publication
    Robust and prototypical immune responses toward influenza vaccines in the high-risk group of Indigenous Australians.
    (2021-10-12)
    Hensen L
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    Nguyen THO
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    Rowntree LC
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    Damelang T
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    Koutsakos M
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    Aban M
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    Hurt A
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    Harland KL
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    Auladell M
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    van de Sandt CE
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    Everitt A
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    Blacker C
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    Oyong DA
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    Loughland, JR
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    Webb JR
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    Wines BD
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    Hogarth PM
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    Flanagan KL
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    Plebanski M
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    Wheatley A
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    Chung AW
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    Kent SJ
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    Miller A
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    Clemens EB
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    Doherty PC
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    Nelson J
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    Davies J
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    Tong SYC
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    Kedzierska K
    Morbidity and mortality rates from seasonal and pandemic influenza occur disproportionately in high-risk groups, including Indigenous people globally. Although vaccination against influenza is recommended for those most at risk, studies on immune responses elicited by seasonal vaccines in Indigenous populations are largely missing, with no data available for Indigenous Australians and only one report published on antibody responses in Indigenous Canadians. We recruited 78 Indigenous and 84 non-Indigenous Australians vaccinated with the quadrivalent influenza vaccine into the Looking into InFluenza T cell immunity - Vaccination cohort study and collected blood to define baseline, early (day 7), and memory (day 28) immune responses. We performed in-depth analyses of T and B cell activation, formation of memory B cells, and antibody profiles and investigated host factors that could contribute to vaccine responses. We found activation profiles of circulating T follicular helper type-1 cells at the early stage correlated strongly with the total change in antibody titers induced by vaccination. Formation of influenza-specific hemagglutinin-binding memory B cells was significantly higher in seroconverters compared with nonseroconverters. In-depth antibody characterization revealed a reduction in immunoglobulin G3 before and after vaccination in the Indigenous Australian population, potentially linked to the increased frequency of the G3m21* allotype. Overall, our data provide evidence that Indigenous populations elicit robust, broad, and prototypical immune responses following immunization with seasonal inactivated influenza vaccines. Our work strongly supports the recommendation of influenza vaccination to protect Indigenous populations from severe seasonal influenza virus infections and their subsequent complications.