Please use this identifier to cite or link to this item: https://hdl.handle.net/10137/8259
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dc.contributor.authorSecombe, Paulen
dc.contributor.authorWoodman, Richarden
dc.contributor.authorChan, Seanen
dc.contributor.authorPilcher, Daviden
dc.contributor.authorvan Haren, Franken
dc.date.accessioned2020-03-10T02:14:53Zen
dc.date.available2020-03-10T02:14:53Zen
dc.date.issued2020-03en
dc.identifier.citationCritical care and resuscitation : journal of the Australasian Academy of Critical Care Medicine 2020-03; 22(1): 35-44en
dc.identifier.issn1441-2772en
dc.identifier.urihttps://hdl.handle.net/10137/8259en
dc.description.abstractThe apparent survival benefit of being overweight or obese in critically ill patients (the obesity paradox) remains controversial. Our aim is to report on the epidemiology and outcomes of obesity within a large heterogenous critically ill adult population. Retrospective observational cohort study. Intensive care units (ICUs) in Australia and New Zealand. Critically ill patients who had both height and weight recorded between 2010 and 2018. Hospital mortality in each of five body mass index (BMI) strata. Subgroups analysed included diagnostic category, gender, age, ventilation status and length of stay. Data were available for 381 855 patients, 68% of whom were overweight or obese. Increasing level of obesity was associated with lower unadjusted hospital mortality: underweight (11.9%), normal weight (7.7%), overweight (6.4%), class I obesity (5.4%), and class II obesity (5.3%). After adjustment, mortality was lowest for patients with class I obesity (adjusted odds ratio, 0.78; 95% CI, 0.74- 0.82). Adverse outcomes with class II obesity were only seen in patients with cardiovascular and cardiac surgery ICU admission diagnoses, where mortality risk rose with progressively higher BMIs. We describe the epidemiology of obesity within a critically ill Australian and New Zealand population and confirm that some level of obesity is associated with lower mortality, both overall and across a range of diagnostic categories and important subgroups. Further research should focus on potential confounders such as nutritional status and the appropriateness of BMI in isolation as an anthropometric measure in critically ill patients.en
dc.description.provenanceMade available in DSpace on 2020-03-10T02:14:53Z (GMT). No. of bitstreams: 0 Previous issue date: 2020-03en
dc.language.isoengen
dc.titleEpidemiology and outcomes of obese critically ill patients in Australia and New Zealand.en
dc.typeJournal Articleen
dc.identifier.journaltitleCritical care and resuscitation : journal of the Australasian Academy of Critical Care Medicineen
dc.identifier.affiliationIntensive Care Unit, Alice Springs Hospital, Alice Springs, NT, Australia. paul.secombe@nt.gov.au..en
dc.identifier.affiliationCentre for Epidemiology and Biostatistics, Flinders University, Adelaide, SA, Australia..en
dc.identifier.affiliationIntensive Care Unit, Canberra Hospital, Canberra, ACT, Australia..en
dc.identifier.affiliationDepartment of Intensive Care, The Alfred Hospital, Melbourne, VIC, Australia..en
dc.identifier.affiliationIntensive Care Unit, Canberra Hospital, Canberra, ACT, Australia..en
dc.identifier.pubmedurihttps://www.ezpdhcs.nt.gov.au/login?url=https://www.ncbi.nlm.nih.gov/pubmed/32102641en
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