Please use this identifier to cite or link to this item: https://hdl.handle.net/10137/7796
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Title: Case Report: Concurrent Rheumatic Fever and Acute Post-Streptococcal Glomerulonephritis in a High-Burden Setting.
Authors: Nakauyaca, Anna V
Ralph, Anna P
Majoni, William S
Kangaharan, Nadarajah
Citation: The American journal of tropical medicine and hygiene 2019-09-16
Abstract: We report a case of acute rheumatic fever with severe pancarditis occurring simultaneously with probable acute post-streptococcal glomerulonephritis in a previously well, Australian Aboriginal, 29-year-old male. These autoimmune streptococcal sequelae are usually considered pathogenetically distinct, and concurrence has not previously been reported from this high-burden setting. We hypothesize that a single type of infecting group A Streptococcus (StrepA) triggered both autoimmune sequelae. Salient features included mitral and aortic regurgitation that worsened during the acute illness, painful pericarditis, and high troponin; severe acute kidney injury with oliguria, hematuria, and macroalbuminuria; reduced complement (C3); and elevated streptococcal serology. The case highlights important diagnostic and management challenges. It also illustrates the serious morbidity impact of the complications of StrepA.
Click to open PubMed article: https://www.ezpdhcs.nt.gov.au/login?url=https://www.ncbi.nlm.nih.gov/pubmed/31516109
Journal title: The American journal of tropical medicine and hygiene
Publication Date: 2019-09-16
Type: Journal Article
URI: https://hdl.handle.net/10137/7796
DOI: 10.4269/ajtmh.18-0954
Appears in Collections:(a) NT Health Research Collection

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