Please use this identifier to cite or link to this item: https://hdl.handle.net/10137/7670
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dc.contributor.authorHuynh, Ronalden
dc.contributor.authorHyun, Kariceen
dc.contributor.authorD'Souza, Marioen
dc.contributor.authorKangaharan, Nadarajahen
dc.contributor.authorShetty, Pratap Cen
dc.contributor.authorMariani, Justinen
dc.contributor.authorKilian, Jensen
dc.contributor.authorHung, Josephen
dc.contributor.authorRyan, Marken
dc.contributor.authorChew, Derek Pen
dc.contributor.authorBrieger, Daviden
dc.date2019en
dc.date.accessioned2019-07-02T06:47:55Zen
dc.date.available2019-07-02T06:47:55Zen
dc.date.issued2019-06-19en
dc.identifier.citationClinical cardiology 2019-06-19en
dc.identifier.urihttps://hdl.handle.net/10137/7670en
dc.description.abstractAnemia commonly accompanies acute coronary syndromes (ACS) and is associated with poorer outcomes. This study examines the associations between anemia, management and outcomes in an Australian ACS population. This analysis of the CONCORDANCE database included 8665 ACS patients presenting to 41 Australian hospitals. Baseline characteristics, management, and outcomes were compared between patients with anemia (Hb ≤ 130 for males, Hb ≤ 120 g/L for females) and non-anemia. A total of 1880 (21.7%) patients presenting with ACS were anemic. These patients were older (72 years vs 63 years, P < .0001), with higher prevalence of comorbidities. STEMI patients with anemia were less likely to be emergently reperfused with either thrombolytic therapy (22% vs 33%, P < .0001) or primary percutaneous coronary intervention (PCI) (45% vs 51% P = 0.033). For all ACS, anemic patients less frequently received: coronary angiography (63% vs 86%, P < .0001); drug eluting stents if undergoing PCI (50% vs 58%, P < .0001); dual antiplatelet therapy (80% vs 89%, P < .0001) ;and parenteral anticoagulants (82% vs 88%, P < .0001). In hospital complications of heart failure (20% vs 9%, P < .0001), renal failure (13% vs 4%, P < .0001), and re-infarction (4% vs 2%, P = .0006) were more common among anemic patients. There was a near-linear inverse relationship between admission hemoglobin and in hospital mortality. Anemic patients with ACS are a high risk group less likely to undergo invasive and antithrombotic therapy. Further investigation is required to determine if more active treatment of anemic patients presenting with ACS will improve their outcomes.en
dc.language.isoengen
dc.subjectacute coronary syndromeen
dc.subjectanemiaen
dc.subjectanticoagulationen
dc.subjectantiplateletsen
dc.subjectpercutaneous interventionen
dc.titleOutcomes of anemic patients presenting with acute coronary syndrome: An analysis of the Cooperative National Registry of Acute Coronary Care, Guideline Adherence and Clinical Events.en
dc.typeJournal Articleen
dc.identifier.journaltitleClinical cardiologyen
dc.identifier.doi10.1002/clc.23219en
dc.identifier.pubmedidhttps://www.ezpdhcs.nt.gov.au/login?url=https://www.ncbi.nlm.nih.gov/pubmed//31216067en
dc.identifier.orcidhttps://orcid.org/0000-0001-6115-0326en
dc.identifier.affiliationDepartment of Cardiology, Concord Hospital, Sydney, New South Wales, Australia..en
dc.identifier.affiliationANZAC Research Institute, University of Sydney, Sydney, New South Wales, Australia.. Westmead Applied Research Centre (WARC), Faculty of Medicine and Health, University of Sydney, Sydney, New South Wales, Australia..en
dc.identifier.affiliationDepartment of Cardiology, Concord Hospital, Sydney, New South Wales, Australia..en
dc.identifier.affiliationDepartment of Cardiology, Royal Darwin Hospital, Darwin, Northern Territory, Australia..en
dc.identifier.affiliationDepartment of Cardiology, Sutherland Heart Clinic, Sydney, New South Wales, Australia..en
dc.identifier.affiliationDepartment of Cardiology, Alfred Hospital, Melbourne, Victoria, Australia.. Department of Medicine, Central Clinical School, Monash University, Melbourne, Victoria, Australia..en
dc.identifier.affiliationDepartment of Cardiology, Bankstown Hospital, Sydney, New South Wales, Australia..en
dc.identifier.affiliationDepartment of Cardiology, Sir Charles Gairdner Hospital, Perth, Western Australia, Australia..en
dc.identifier.affiliationDepartment of Cardiology, Shoalhaven Hospital, Nowra, New South Wales, Australia..en
dc.identifier.affiliationCardiac Services, Flinders Medical Centre, Adelaide, South Australia, Australia..en
dc.identifier.affiliationDepartment of Cardiology, Concord Hospital, Sydney, New South Wales, Australia..en
dc.identifier.pubmedurihttps://www.ezpdhcs.nt.gov.au/login?url=https://www.ncbi.nlm.nih.gov/pubmed//31216067en
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