Please use this identifier to cite or link to this item: https://hdl.handle.net/10137/5585
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dc.contributor.authorCrowe, Amy-
dc.contributor.authorMcMahon, Nicole-
dc.contributor.authorCurrie, Bart J-
dc.contributor.authorBaird, Robert W-
dc.date2014-
dc.date.accessioned2018-05-15T23:01:16Z-
dc.date.available2018-05-15T23:01:16Z-
dc.date.issued2014-08-
dc.identifier.citationInternational journal of antimicrobial agents 2014-08; 44(2): 160-2-
dc.identifier.urihttps://hdl.handle.net/10137/5585-
dc.description.abstractBurkholderia pseudomallei is a saprophytic Gram-negative bacterium responsible for the tropical infectious disease melioidosis. Melioidosis is endemic to northern Australia and Southeast Asia. In this study, 234 isolates of B. pseudomallei obtained from the first positive clinical specimen from 234 consecutive patients diagnosed with melioidosis between October 2009 and September 2012 were reviewed. All isolates were susceptible to meropenem and ceftazidime. In total, 226 isolates (96.6%) were susceptible to doxycycline and 232 (99.1%) were susceptible to trimethoprim/sulfamethoxazole (TMP/SMX; co-trimoxazole). Primary resistance of B. pseudomallei to ceftazidime and/or meropenem is exceedingly rare and clinicians can be confident in the current treatment guidelines for melioidosis. Whether the very low rates of TMP/SMX resistance seen in Australia reflect the global situation requires further studies using Etest, especially to clarify the rate of resistance in Thailand.-
dc.description.provenanceMade available in DSpace on 2018-05-15T23:01:16Z (GMT). No. of bitstreams: 0 Previous issue date: 2014-08en
dc.language.isoeng-
dc.subjectAntimicrobial susceptibility-
dc.subjectBurkholderia pseudomallei-
dc.subjectMelioidosis-
dc.titleCurrent antimicrobial susceptibility of first-episode melioidosis Burkholderia pseudomallei isolates from the Northern Territory, Australia.-
dc.typeJournal Article-
dc.typeResearch Support, Non-U.S. Gov't-
dc.identifier.journaltitleInternational journal of antimicrobial agents-
dc.identifier.doi10.1016/j.ijantimicag.2014.04.012-
dc.identifier.pubmedidhttps://www.ezpdhcs.nt.gov.au/login?url=https://www.ncbi.nlm.nih.gov/pubmed/24924662-
dc.subject.meshAnti-Bacterial Agents-
dc.subject.meshBurkholderia pseudomallei-
dc.subject.meshCeftazidime-
dc.subject.meshDrug Resistance, Bacterial-
dc.subject.meshHumans-
dc.subject.meshMelioidosis-
dc.subject.meshMicrobial Sensitivity Tests-
dc.subject.meshNorthern Territory-
dc.subject.meshRoot Cause Analysis-
dc.subject.meshThienamycins-
dc.subject.meshTrimethoprim, Sulfamethoxazole Drug Combination-
dc.identifier.affiliationMicrobiology Department, Royal Darwin Hospital, Rocklands Drive, Tiwi, NT 0810, Australia; Infectious Diseases Department, Royal Darwin Hospital, Rocklands Drive, Tiwi, NT 0810, Australia..-
dc.identifier.affiliationMicrobiology Department, Royal Darwin Hospital, Rocklands Drive, Tiwi, NT 0810, Australia..-
dc.identifier.affiliationInfectious Diseases Department, Royal Darwin Hospital, Rocklands Drive, Tiwi, NT 0810, Australia; Global and Tropical Health Division, Menzies School of Health Research, Darwin, NT 0810, Australia..-
dc.identifier.affiliationMicrobiology Department, Royal Darwin Hospital, Rocklands Drive, Tiwi, NT 0810, Australia; Infectious Diseases Department, Royal Darwin Hospital, Rocklands Drive, Tiwi, NT 0810, Australia. Electronic address: rob.baird@nt.gov.au..-
dc.identifier.pubmedurihttps://www.ezpdhcs.nt.gov.au/login?url=https://www.ncbi.nlm.nih.gov/pubmed/24924662-
Appears in Collections:(a) NT Health Research Collection

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