Please use this identifier to cite or link to this item: https://hdl.handle.net/10137/5545
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dc.contributor.authorAndersson Pen
dc.contributor.authorTong SYCen
dc.contributor.authorLilliebridge RAen
dc.contributor.authorBrenner NCen
dc.contributor.authorMartin LMen
dc.contributor.authorSpencer Een
dc.contributor.authorDelima Jen
dc.contributor.authorSingh Gen
dc.contributor.authorMcCann Fen
dc.contributor.authorHudson Cen
dc.contributor.authorJohns Ten
dc.contributor.authorGiffard PMen
dc.date2013en
dc.date.accessioned2018-05-15T23:01:09Zen
dc.date.available2018-05-15T23:01:09Zen
dc.date.issued2014-09en
dc.identifier.citationJournal of the Pediatric Infectious Diseases Society 2014-09; 3(3): 189-96en
dc.identifier.urihttps://hdl.handle.net/10137/5545en
dc.description.abstractThe detection of a sexually transmitted infection (STI) agent in a urine specimen from a young child is regarded as an indicator of sexual contact. False positives may conceivably arise from the transfer of environmental contaminants in clinic toilet or bathroom facilities into urine specimens. The potential for contamination of urine specimens with environmental STI nucleic acid was tested empirically in the male and female toilets or bathrooms at 10 Northern Territory (Australia) clinics, on 7 separate occasions at each. At each of the 140 experiments, environmental contamination with Chlamydia trachomatis, Neisseria gonorrhoeae, and Trichomonas vaginalis nucleic acid contamination was determined by swabbing 10 locations, and urine collection was simulated 5 times, using a (1) synthetic urine surrogate and (2) a standardized finger contamination procedure. The most contaminated toilets and bathrooms were in remote Indigenous communities. No contamination was found in the Northern Territory Government Sexual Assault Referral Centre clinics, and intermediate levels of contamination were found in sexual health clinics and in clinics in regional urban centres. The frequency of surrogate urine sample contamination was low but non-zero. For example, 4 of 558 of the urine surrogate specimens from remote clinics were STI positive. This is by far the largest study addressing the potential environmental contamination of urine samples with STI agents. Positive STI tests arising from environmental contamination of urine specimens cannot be ruled out. The results emphasize that urine specimens from young children taken for STI testing should be obtained by trained staff in clean environments, and duplicate specimens should be obtained if possible.en
dc.language.isoengen
dc.subjectcontaminationen
dc.subjectdiagnosisen
dc.subjectfalse positiveen
dc.subjectsexually transmitted infectionen
dc.subjecturineen
dc.titleMultisite Direct Determination of the Potential for Environmental Contamination of Urine Samples Used for Diagnosis of Sexually Transmitted Infections.en
dc.typeJournal Articleen
dc.identifier.journaltitleJournal of the Pediatric Infectious Diseases Societyen
dc.identifier.doi10.1093/jpids/pit085en
dc.identifier.pubmedidhttps://www.ezpdhcs.nt.gov.au/login?url=https://www.ncbi.nlm.nih.gov/pubmed//25349693en
dc.identifier.affiliationDivision of Global and Tropical Health, Menzies School of Health Research, Charles Darwin University, Tiwi, Northern Territory, Australia..en
dc.identifier.affiliationDivision of Global and Tropical Health, Menzies School of Health Research, Charles Darwin University, Tiwi, Northern Territory, Australia..en
dc.identifier.affiliationDivision of Global and Tropical Health, Menzies School of Health Research, Charles Darwin University, Tiwi, Northern Territory, Australia..en
dc.identifier.affiliationDivision of Global and Tropical Health, Menzies School of Health Research, Charles Darwin University, Tiwi, Northern Territory, Australia..en
dc.identifier.affiliationRoyal Darwin Hospital, Tiwi, Australia..en
dc.identifier.affiliationRoyal Darwin Hospital, Tiwi, Australia..en
dc.identifier.affiliationNorthern Territory Government Sexual Assault Referral Centre (Alice Springs), Australia..en
dc.identifier.affiliationRoyal Darwin Hospital, Tiwi, Australia Division of Child Health, Menzies School of Health Research, Charles Darwin University, Tiwi, Australia..en
dc.identifier.affiliationNorthern Territory Government Sexual Assault Referral Centre (Darwin), Casuarina Health Service Centre, Casuarina Northern Territory, Australia..en
dc.identifier.affiliationNorthern Territory Government Sexual Assault Referral Centre (Alice Springs), Australia..en
dc.identifier.affiliationNorthern Territory Government Sexual Assault Referral Centre (Darwin), Casuarina Health Service Centre, Casuarina Northern Territory, Australia..en
dc.identifier.affiliationDivision of Global and Tropical Health, Menzies School of Health Research, Charles Darwin University, Tiwi, Northern Territory, Australia..en
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