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dc.contributor.authorLawton PDen
dc.contributor.authorCunningham Jen
dc.contributor.authorZhao Yen
dc.contributor.authorGray NAen
dc.contributor.authorChatfield MDen
dc.contributor.authorBaade PDen
dc.contributor.authorMurali Ken
dc.contributor.authorJose MDen
dc.identifier.citationThe Medical journal of Australia 2015-03-02; 202(4): 200-4en
dc.description.abstractTo compare mortality rates for Indigenous and non-Indigenous Australians commencing renal replacement therapy (RRT) over time and by categories of remoteness of place of residence. An observational cohort study of Australia and New Zealand Dialysis and Transplant Registry (ANZDATA) data on Indigenous and non-Indigenous Australians registered with ANZDATA who commenced RRT from 1 January 1995 to 31 December 2009 and were followed until 31 December 2011. Five-year all-cause mortality for Indigenous and non-Indigenous patients in three cohorts (1995-1999, 2000-2004 and 2005-2009) and five remoteness (of place of residence) categories. Indigenous patients were younger, more likely to have diabetes, be referred late and be from a more remote area than non-Indigenous patients. Age and comorbid conditions increased with successive cohorts for both groups. Unadjusted analysis (using the log-rank test) showed an increased risk of death for Indigenous patients in the 1995-1999 (P = 0.02) and 2000-2004 (P = 0.03) cohorts, but not for the 2005-2009 cohort (P = 0.7). However, a Cox proportional hazards model adjusted for covariates (age, sex, late referral and comorbid conditions [diabetes, coronary artery disease, peripheral vascular disease, cerebrovascular disease, lung disease], and body mass index < 18.5 kg/m(2) and > 30 kg/m(2)) showed the following Indigenous:non-Indigenous hazard ratios (with 95% CIs) for major capital cities: 1995-1999, 1.47 (1.21-1.79); 2000-2004, 1.35 (1.12-1.63); and 2005-2009, 1.37 (1.14-1.66). Although unadjusted analysis suggests that the survival gap between Indigenous and non-Indigenous patients receiving RRT has closed, there remains a significant disparity in survival after adjusting for the variables considered in our study.en
dc.titleSurvival of Indigenous Australians receiving renal replacement therapy: closing the gap?en
dc.typeJournal Articleen
dc.typeMulticenter Studyen
dc.typeObservational Studyen
dc.typeResearch Support, Non-U.S. Gov'ten
dc.identifier.journaltitleThe Medical journal of Australiaen
dc.subject.meshCause of Deathen
dc.subject.meshFollow-Up Studiesen
dc.subject.meshKidney Failure, Chronicen
dc.subject.meshMiddle Ageden
dc.subject.meshNew Zealanden
dc.subject.meshProportional Hazards Modelsen
dc.subject.meshRenal Replacement Therapyen
dc.subject.meshRetrospective Studiesen
dc.subject.meshSurvival Rateen
dc.subject.meshTime Factorsen
dc.subject.meshPopulation Groupsen
dc.identifier.affiliationMenzies School of Health Research, Darwin, NT, Australia.
dc.identifier.affiliationMenzies School of Health Research, Darwin, NT, Australia..en
dc.identifier.affiliationNorthern Territory Department of Health, Darwin, NT, Australia..en
dc.identifier.affiliationNambour General Hospital, Nambour, QLD, Australia..en
dc.identifier.affiliationMenzies School of Health Research, Darwin, NT, Australia..en
dc.identifier.affiliationCancer Council Queensland, Brisbane, QLD, Australia..en
dc.identifier.affiliationWollongong Hospital, Wollongong, NSW, Australia..en
dc.identifier.affiliationUniversity of Tasmania, Hobart, TAS, Australia..en
Appears in Collections:(a) NT Health Research Collection

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