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dc.contributor.authorDavis Ken
dc.contributor.authorRemenyi Ben
dc.contributor.authorDraper ADKen
dc.contributor.authorDos Santos Jen
dc.contributor.authorBayley Nen
dc.contributor.authorParatz Een
dc.contributor.authorReeves Ben
dc.contributor.authorAppelbe Aen
dc.contributor.authorCochrane Aen
dc.contributor.authorJohnson TDen
dc.contributor.authorKorte LMen
dc.contributor.authorDo Rosario IMen
dc.contributor.authorDa Silva Almeida ITen
dc.contributor.authorRoberts KVen
dc.contributor.authorCarapetis JRen
dc.contributor.authorFrancis JRen
dc.identifier.citationThe Medical journal of Australia 2018-04-16; 208(7): 303-307en
dc.description.abstractTo determine the prevalence of rheumatic heart disease (RHD) in school-aged children and young people in Timor-Leste. Prospective cross-sectional survey. Echocardiography was performed by Australian cardiologists to determine the presence of RHD. Demographic data were also collected. Patients in whom RHD was detected were entered into a register to allow monitoring of adherence to secondary prophylaxis; the first dose of benzathine penicillin G (BPG) was administered on the day of screening. Schools in urban (Dili) and rural (Ermera) Timor-Leste. School students aged 5-20 years. Definite and borderline RHD, as defined by World Heart Federation echocardiographic criteria. 1365 participants were screened; their median age was 11 years (IQR, 9-14 years), and 53% were girls. The estimated prevalence of definite RHD was 18.3 cases per 1000 population (95% CI, 12.3-27.0 per 1000), and of definite or borderline RHD 35.2 per 1000 (95% CI, 26.5-46.4 per 1000). Definite (adjusted odds ratio [aOR], 3.5; 95% CI, 1.3-9.4) and definite or borderline RHD (aOR, 2.7; 95% CI, 1.4-5.2) were more prevalent among girls than boys. Eleven children (0.8%) had congenital heart disease. Of the 25 children in whom definite RHD was identified, 21 (84%) received education and a first dose of BPG on the day of screening; all 25 have since received education about primary care for RHD and have commenced penicillin prophylaxis. The rates of RHD in Timor-Leste are among the highest in the world, and prevalence is higher among girls than boys. Community engagement is essential for ensuring follow-up and the effective delivery of secondary prophylaxis.en
dc.subjectGlobal health issuesen
dc.subjectHealth inequalitiesen
dc.subjectRheumatic feveren
dc.titleRheumatic heart disease in Timor-Leste school students: an echocardiography-based prevalence study.en
dc.typeJournal Articleen
dc.identifier.journaltitleThe Medical journal of Australiaen
dc.identifier.affiliationRoyal Darwin Hospital, Darwin, NT
dc.identifier.affiliationRoyal Darwin Hospital, Darwin, NT..en
dc.identifier.affiliationCentre for Disease Control, Northern Territory Department of Health, Darwin, NT..en
dc.identifier.affiliationMaluk Timor, Dili, Timor-Leste..en
dc.identifier.affiliationEast Timor Hearts Fund, Melbourne, VIC..en
dc.identifier.affiliationSt Vincent's Hospital, Melbourne, VIC..en
dc.identifier.affiliationCairns Hospital, Cairns, QLD..en
dc.identifier.affiliationGeelong Cardiology Group, Barwon Health, Geelong, VIC..en
dc.identifier.affiliationMonash Medical Centre Clayton, Melbourne, VIC..en
dc.identifier.affiliationTelethon Kids Institute, University of Western Australia, Perth, WA..en
dc.identifier.affiliationPaediatric WA Country Health Service - Kimberley, Broome, WA..en
dc.identifier.affiliationHospital Nacional Guido Valadares, Dili, Timor-Leste..en
dc.identifier.affiliationHospital Nacional Guido Valadares, Dili, Timor-Leste..en
dc.identifier.affiliationRoyal Darwin Hospital, Darwin, NT..en
dc.identifier.affiliationTelethon Kids Institute, University of Western Australia, Perth, WA..en
dc.identifier.affiliationRoyal Darwin Hospital, Darwin, NT..en
Appears in Collections:(a) NT Health Research Collection

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