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Title: Meningitis and a febrile vomiting illness caused by Echovirus type 4, Northern Territory, Australia
Authors: Markey, Peter
Davis, Josh
Harnett, Gerry
Williams, Simon
Speers, David
Citation: Markey PG, Davis JS, Harnett GB, Williams SH, Speers DJ. Meningitis and a febrile vomiting illness caused by Echovirus type 4, Northern Territory, Australia. Emerg Infect Dis 2010 Jan;16(1):63-68
Publisher: Centers for Disease Control and Prevention, Atlanta, Georgia
Abstract: In July 2007, a cluster of meningitis cases caused by an echovirus 4 strain was detected in 1 indigenous community in the Top End of the Northern Territory of Australia. Illness was characterized by fever, vomiting, and headache. Over the next 4 months, additional cases of meningitis and the fever and vomiting syndrome emerged in other indigenous communities and subsequently in the major urban center of Darwin. We describe the epidemiology of 95 laboratory-confirmed meningitis cases and conclude that the epidemic fever and vomiting syndrome was caused by the same enterovirus. Nucleotide sequencing of the whole genome verified this enterovirus (AUS250G) as a strain of echovirus type 4. Viral protein 1 nucleotide sequencing demonstrated 96% homology with an echovirus 4 strain responsible for a large outbreak of meningitis in the Yanbian Prefecture of China in 1996.
Description: This article can be freely accessed at the URI
Publication Date: 2010-01
ISSN: 1080-6059
Type: Journal Article
Appears in Collections:(b) NT General Collection

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