Please use this identifier to cite or link to this item:
Title: Uncertainty and the unmet informational needs of patients with cancer of unknown primary (CUP): a cross-sectional multi-site study.
Authors: Guccione, Lisa
Fisher, Krista
Mileshkin, Linda
Tothill, Richard
Bowtell, David
Quinn, Stephen
DeFazio, Anna
Karapetis, Chris S
Wilcken, Nicholas
Singh, Madhu
Steer, Christopher
Gao, Bo
Warren, Mark
Collins, Ian M
Karanth, Narayan
Bryant, Cindy
Schofield, Penelope
Citation: © 2022. The Author(s).
Support Care Cancer. 2022 Jul 9. doi: 10.1007/s00520-022-07228-7.
Abstract: OBJECTIVE: This study aimed to determine the healthcare experiences, quality of life, and psychosocial needs of patients with cancer of unknown primary (CUP) early after diagnosis; comparing their experiences to patients with advanced cancer of a known primary (non-CUP control patients) and published general population reference data where available. METHODS: This study was a cross-sectional, multi-site study comparing CUP patients (n = 139) compared to non-CUP controls (n = 45). Demographic, clinical information and patient-reported outcome questionnaire data were collected at baseline. RESULTS: Differences in healthcare experienced were found between CUP and non-CUP controls with CUP patients reporting higher scores for unmet medical communication/information needs compared with non-CUP control patients (p = 0.013) as well as greater uncertainty in illness (p = 0.042). Whilst no differences were found between CUP and non-CUP controls on the EORTC and PROMIS measures, of those that 'received written information about your cancer…' and asked '…how useful was it?' fewer CUP patients reported finding the information useful 40% vs 61%, and more were likely to not have received written information at all 59% vs 32%; (p = 0.002). Additionally, of those that found information about their cancer online, fewer patients with CUP reported finding it useful 32% vs 48% control patients (p = 0.005). CONCLUSIONS: CUP patients have unmet medical communication/information needs and greater uncertainty in illness but do not differ in health-related quality of life domains compared to patients with advanced cancer of a known primary.
Click to open Pubmed Article:
Journal title: Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer
Publication Date: 2022-07-09
Type: Journal Article
DOI: 10.1007/s00520-022-07228-7
Orcid: 0000-0002-1408-3615
Appears in Collections:(a) NT Health Research Collection

Files in This Item:
There are no files associated with this item.

Items in ePublications are protected by copyright, with all rights reserved, unless otherwise indicated.

Google Media

Google ScholarTM

Who's citing


PubMed References

Who's citing