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Title: 'Neurosyphilis in the Northern Territory of Australia: a clinical guideline'.
Authors: Birrell, Johanna M
Lowe, Michael
Gunathilake, Manoji
Krause, Vicki
Citation: This article is protected by copyright. All rights reserved.
Intern Med J. 2022 Jan 9. doi: 10.1111/imj.15691.
Abstract: BACKGROUND: The Northern Territory (NT) of Australia is currently experiencing a syphilis epidemic. Neurosyphilis is commonly considered in the differential diagnosis for patients presenting with neurologic conditions such as dementia and stroke in the NT. AIMS: To explore the local epidemiologic, diagnostic and treatment complexities of neurosyphilis in the NT and produce a guideline for clinical practice. METHODS: A database search was undertaken and local and global neurosyphilis guidelines were analysed. A guideline was created based on findings of the critical review and consultation with local multi-disciplinary experts. RESULTS: Neurosyphilis is frequently encountered in the NT but studies suggest it is often under-treated. Dementia is the most common clinical presentation locally. Establishing a diagnosis of neurosyphilis is complex and requires stepwise evaluation of clinical, laboratory and radiological findings. CONCLUSIONS: A clinical guideline and algorithm have been developed for the diagnosis and management of patients with neurosyphilis. This article is protected by copyright. All rights reserved.
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Journal title: Internal medicine journal
Publication Date: 2022-01-09
Type: Journal Article
DOI: 10.1111/imj.15691
Orcid: 0000-0002-5142-313X
Appears in Collections:(a) NT Health Research Collection

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