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Title: Type 2 diabetes after a pregnancy with gestational diabetes among first nations women in Australia: The PANDORA study.
Authors: Wood AJ
Boyle JA
Barr ELM
Barzi F
Hare MJL
Titmuss A
Longmore DK
Death E
Kelaart J
Kirkwood M
Graham S
Connors C
Moore E
O'Dea K
Oats, Jeremy J N
McIntyre HD
Zimmet PZ
Brown A
Shaw JE
Maple-Brown LJ
Citation: Copyright © 2021 The Author(s). Published by Elsevier B.V. All rights reserved.
Diabetes Res Clin Pract. 2021 Oct 13;181:109092. doi: 10.1016/j.diabres.2021.109092.
Abstract: AIMS: To determine among First Nations and Europid pregnant women the cumulative incidence and predictors of postpartum type 2 diabetes and prediabetes and describe postpartum cardiovascular disease (CVD) risk profiles. METHODS: PANDORA is a prospective longitudinal cohort of women recruited in pregnancy. Ethnic-specific rates of postpartum type 2 diabetes and prediabetes were reported for women with diabetes in pregnancy (DIP), gestational diabetes (GDM) or normoglycaemia in pregnancy over a short follow-up of 2.5 years (n = 325). Pregnancy characteristics and CVD risk profiles according to glycaemic status, and factors associated with postpartum diabetes/prediabetes were examined in First Nations women. RESULTS: The cumulative incidence of postpartum type 2 diabetes among women with DIP or GDM were higher for First Nations women (48%, 13/27, women with DIP, 13%, 11/82, GDM), compared to Europid women (nil DIP or GDM p < 0.001). Characteristics associated with type 2 diabetes/prediabetes among First Nations women with GDM/DIP included, older age, multiparity, family history of diabetes, higher glucose values, insulin use and body mass index (BMI). CONCLUSIONS: First Nations women experience a high incidence of postpartum type 2 diabetes after GDM/DIP, highlighting the need for culturally responsive policies at an individual and systems level, to prevent diabetes and its complications.
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Journal title: Diabetes research and clinical practice
Volume: 181
Pages: 109092
Publication Date: 2021-10-13
Type: Journal Article
DOI: 10.1016/j.diabres.2021.109092
Appears in Collections:(a) NT Health Research Collection

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