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|Title:||An outbreak of serotype-1 sequence type 306 invasive pneumococcal disease in an Australian Indigenous population.|
|Authors:||Cook, Heather M|
Giele, Caroline M
Jayasinghe, Sanjay H
Krause, Vicki L
|Citation:||© Commonwealth of Australia CC BY-NC-ND.|
Commun Dis Intell (2018). 2020 Sep 15;44. doi: 10.33321/cdi.2020.44.66.
|Abstract:||Between 2010 and 2013, an outbreak of serotype-1 sequence type 306 (ST306) invasive pneumococcal disease (IPD) occurred primarily in remote locations of Northern and Central Australia. This is a descriptive study of the epidemiology of the outbreak using nationwide IPD surveillance data, supplemented with more detailed data held by affected jurisdictions, and of the response to the outbreak, including vaccination strategies. In the year the outbreak peaked (2011), serotype-1 IPD incidence was over 30-fold higher in the affected regions than in the rest of Australia (incidence rate ratio: 30.7 [95% CI 20.1-48.9]). The study includes 245 cases of serotype-1 IPD from the outbreak regions, with 75.5% identified as Indigenous. No reported cases of serotype-1 IPD occurred in young children who had completed either a 10- or 13-valent pneumococcal conjugate vaccine schedule. However serotype-1 IPD did occur in older children who had previously received 23-valent pneumococcal polysaccharide vaccine. Development of public-health-focused national IPD management guidelines, including suitable vaccine strategies for consistent use nationwide, could potentially decrease the duration and intensity of similar outbreaks in the future.|
|Click to open Pubmed Article:||https://pubmed-ncbi-nlm-nih-gov.www.ezpdhcs.nt.gov.au/32988336/|
|Journal title:||Communicable diseases intelligence (2018)|
|Appears in Collections:||(a) NT Health Research Collection|
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