Einsiedel, Lloyd

Chiong, Fabian

Jersmann, Hubertus

Taylor, Graham

2021-01-06

Erratum: Correction to: Human T-cell leukaemia virus type 1 associated pulmonary disease: clinical and pathological features of an under-recognised complication of HTLV-1 infection SEE THE DOI FIELD BELOW TO ACCESS ERRATUM FOR THIS ARTICLE

The lung is one of several organs that can be affected by HTLV-1 mediated inflammation. Pulmonary inflammation associated with HTLV-1 infection involves the interstitium, airways and alveoli, resulting in several clinical entities including interstitial pneumonias, bronchiolitis and alveolitis, depending on which structures are most affected. Augmentation of the inflammatory effects of HTLV-1 infected lymphocytes by recruitment of other inflammatory cells in a positive feedback loop is likely to underlie the pathogenesis of HTLV-1 associated pulmonary disease, as has been proposed for HTLV-1 associated myelopathy. In contrast to the conclusions of early case series, HTLV-1 associated pulmonary disease can be associated with significant parenchymal damage, which may progress to bronchiectasis where this involves the airways. Based on our current understanding of HTLV-1 associated pulmonary disease, diagnostic criteria are proposed.

Department of Medicine, Alice Springs Hospital, Alice Springs, Northern Territory, 0870, Australia. lloyd.einsiedel@nt.gov.au.

Department of Medicine, Alice Springs Hospital, Alice Springs, Northern Territory, 0870, Australia.

Department of Respiratory Medicine, Faculty of Medicine, Royal Adelaide Hospital, Adelaide, Australia.

Department of Infectious Diseases, Faculty of Medicine, Imperial College London, London, UK.

Retrovirology. 2021 Jan 6;18(1):1. doi: 10.1186/s12977-020-00543-z.

0000-0002-2517-6083

https://pubmed.ncbi.nlm.nih.gov/33407607/?otool=iaurydwlib

18

Human T-cell leukaemia virus type 1 associated pulmonary disease: clinical and pathological features of an under-recognised complication of HTLV-1 infection.

Journal Article

Publication