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dc.contributor.authorMcLean Aen
dc.contributor.authorKatz Men
dc.contributor.authorOats Jen
dc.contributor.authorWang Zen
dc.contributor.authorBarr Een
dc.contributor.authorMaple-Brown LJen
dc.identifier.citation© 2021 The Royal Australian and New Zealand College of Obstetricians and Gynaecologists.en
dc.identifier.citationAust N Z J Obstet Gynaecol. 2021 Jan 3. doi: 10.1111/ajo.13281.en
dc.description.abstractBACKGROUND: Antenatal ultrasound is used frequently in pregnancies complicated by hyperglycaemia; however, it is unclear which measurements have the greatest association with adverse neonatal outcomes. AIM: To assess the association between third trimester ultrasound parameters with adverse neonatal outcomes in pregnancies complicated by hyperglycaemia. METHOD: All pregnant women with gestational or type 2 diabetes who birthed in a regional hospital over 12 months were included. A composite adverse neonatal outcome was defined by one or more: admission to special care nursery, acidosis, hypoglycaemia, jaundice, shoulder dystocia, respiratory distress syndrome or 5-minute Apgar score < 5. Logistic regression was used to determine odds ratios (OR) for an adverse neonatal outcome, according to pre-specified cut points in both lower and upper percentiles of abdominal circumference (AC) and estimated fetal weight (EFW). RESULTS: Of 275 births an adverse outcome occurred in 122 (44%). Unadjusted OR (95% CI) for AC ≤30(th) was 3.2 (1.1-8.8) and >95(th) percentile was 3.1 (1.5-6.0) compared with the reference group of 31-70(th) percentile. Unadjusted OR for EFW ≤30(th) was 1.5 (0.7-3.1) and >95(th) percentile was 3.0 (1.4-6.3). After adjusting for maternal age, body mass index, diabetes type, ethnicity, gravidity, mode of delivery and gestation at birth the OR (95% CI) were as follows: AC ≤30(th) percentile, 3.7 (1.1-12.4); AC >95(th) , 2.2 (1.1-4.8); EFW ≤30(th) , 2.6 (1.1-6.1); EFW >95(th) , 2.5 (1.1-6.1). CONCLUSION: An AC and EFW up to the 30(th) percentile may pose just as great a risk to the fetus as an AC or EFW >95(th) percentile in pregnancies complicated by hyperglycaemia.en
dc.titleRethinking third trimester ultrasound measurements and risk of adverse neonatal outcomes in pregnancies complicated by hyperglycaemia: A retrospective study.en
dc.typeJournal Articleen
dc.identifier.journaltitleThe Australian & New Zealand journal of obstetrics & gynaecologyen
dc.description.affiliationDepartment of Endocrinology, Cairns Diabetes Centre, Cairns, Queensland, Australia.en
dc.description.affiliationWellbeing and Chronic Preventable Diseases Division, Menzies School of Health Research, Darwin, Northern Territory, Australia.en
dc.description.affiliationMelbourne School of Population and Global Health, University of Melbourne, Melbourne, Victoria, Australia.en
dc.description.affiliationDepartment of Endocrinology, Royal Darwin Hospital, Darwin, Northern Territory, Australia.en
local.issue.number1479-828X (Electronic)-
local.issue.number0004-8666 (Linking)-
Appears in Collections:(a) NT Health Research Collection

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