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https://hdl.handle.net/10137/11444
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DC Field | Value | Language |
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dc.contributor.author | Grivas R | en |
dc.contributor.author | Freeman K | en |
dc.contributor.author | Baird RW | en |
dc.date.accessioned | 2020-10-20T05:46:46Z | en |
dc.date.available | 2020-10-20T05:46:46Z | en |
dc.date.issued | 2014-12 | en |
dc.identifier.citation | Pathology. 2014 Dec;46(7):644-8. doi: 10.1097/PAT.0000000000000164. | en |
dc.identifier.other | 0175411 | en |
dc.identifier.uri | https://hdl.handle.net/10137/11444 | en |
dc.description.abstract | A retrospective observational study of human T-lymphotropic virus-1 (HTLV-1) serology requests made to the Northern Territory Government Pathology Service (NTGPS) between 2008 and 2011, was undertaken to review aspects of HTLV-1 sero-epidemiology and performance of the assays. A total of 5686 HTLV-1 serology requests, representing 3555 individual patients, were received during the study period; 368 HTLV-1 confirmed positive serology results were identified from the 3555 individual patients included in the sample. There was a distinct difference in the performance of the two antibody assays in use during this period, with the Serodia particle agglutination having a 5.7% indeterminate positivity rate compared to 18.1% indeterminate positivity rate of the Abbott HTLV 1/2 assay. We believe this is partially a serological anomaly related to current Australian western blot positive interpretative criteria, rather than false positive screening assay results.The majority (99.7%) of positive results occurred in Indigenous patients. The HTLV-1 positive rate varied geographically from a regional high of 51.7%, and falling inversely with distance from Central Australia. Patients with positive serology had a mean age of 49.9 (±13.9) years, with positivity occurring equally in males and females. | en |
dc.language.iso | eng | en |
dc.subject | Adult | en |
dc.subject | Australia | en |
dc.subject | Enzyme-Linked Immunosorbent Assay/methods | en |
dc.subject | Female | en |
dc.subject | HTLV-I Infections/*virology | en |
dc.subject | Human T-lymphotropic virus 1/*isolation & purification | en |
dc.subject | Humans | en |
dc.subject | Male | en |
dc.subject | Middle Aged | en |
dc.subject | Northern Territory | en |
dc.subject | Retrospective Studies | en |
dc.subject | Serology/methods | en |
dc.title | Human T-lymphotropic virus-1 serology in the Northern Territory: 2008-2011. | en |
dc.type | Journal Article | en |
dc.publisher.place | England | en |
dc.identifier.journaltitle | Pathology | en |
dc.identifier.doi | 10.1097/PAT.0000000000000164 | en |
dc.identifier.pubmeduri | https://www.ezpdhcs.nt.gov.au/login?url=https://www.ncbi.nlm.nih.gov/pubmed/25393257 | en |
dc.format.pages | 644-8 | en |
dc.description.affiliation | 1Royal Darwin Hospital 2Pathology Department, Northern Territory Government Pathology Service, Darwin, NT, Australia. | en |
dc.source.volume | 46 | en |
local.issue.number | 1465-3931 (Electronic) | - |
local.issue.number | 0031-3025 (Linking) | - |
Appears in Collections: | (a) NT Health Research Collection |
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