Please use this identifier to cite or link to this item: https://hdl.handle.net/10137/11444
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dc.contributor.authorGrivas Ren
dc.contributor.authorFreeman Ken
dc.contributor.authorBaird RWen
dc.date.accessioned2020-10-20T05:46:46Zen
dc.date.available2020-10-20T05:46:46Zen
dc.date.issued2014-12en
dc.identifier.citationPathology. 2014 Dec;46(7):644-8. doi: 10.1097/PAT.0000000000000164.en
dc.identifier.other0175411en
dc.identifier.urihttps://hdl.handle.net/10137/11444en
dc.description.abstractA retrospective observational study of human T-lymphotropic virus-1 (HTLV-1) serology requests made to the Northern Territory Government Pathology Service (NTGPS) between 2008 and 2011, was undertaken to review aspects of HTLV-1 sero-epidemiology and performance of the assays. A total of 5686 HTLV-1 serology requests, representing 3555 individual patients, were received during the study period; 368 HTLV-1 confirmed positive serology results were identified from the 3555 individual patients included in the sample. There was a distinct difference in the performance of the two antibody assays in use during this period, with the Serodia particle agglutination having a 5.7% indeterminate positivity rate compared to 18.1% indeterminate positivity rate of the Abbott HTLV 1/2 assay. We believe this is partially a serological anomaly related to current Australian western blot positive interpretative criteria, rather than false positive screening assay results.The majority (99.7%) of positive results occurred in Indigenous patients. The HTLV-1 positive rate varied geographically from a regional high of 51.7%, and falling inversely with distance from Central Australia. Patients with positive serology had a mean age of 49.9 (±13.9) years, with positivity occurring equally in males and females.en
dc.language.isoengen
dc.subjectAdulten
dc.subjectAustraliaen
dc.subjectEnzyme-Linked Immunosorbent Assay/methodsen
dc.subjectFemaleen
dc.subjectHTLV-I Infections/*virologyen
dc.subjectHuman T-lymphotropic virus 1/*isolation & purificationen
dc.subjectHumansen
dc.subjectMaleen
dc.subjectMiddle Ageden
dc.subjectNorthern Territoryen
dc.subjectRetrospective Studiesen
dc.subjectSerology/methodsen
dc.titleHuman T-lymphotropic virus-1 serology in the Northern Territory: 2008-2011.en
dc.typeJournal Articleen
dc.publisher.placeEnglanden
dc.identifier.journaltitlePathologyen
dc.identifier.doi10.1097/PAT.0000000000000164en
dc.identifier.pubmedurihttps://www.ezpdhcs.nt.gov.au/login?url=https://www.ncbi.nlm.nih.gov/pubmed/25393257en
dc.format.pages644-8en
dc.description.affiliation1Royal Darwin Hospital 2Pathology Department, Northern Territory Government Pathology Service, Darwin, NT, Australia.en
dc.source.volume46en
local.issue.number1465-3931 (Electronic)-
local.issue.number0031-3025 (Linking)-
Appears in Collections:(a) NT Health Research Collection

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