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Title: Melioidosis: An Australian Perspective.
Authors: Smith S
Hanson J
Currie BJ
Citation: Trop Med Infect Dis. 2018 Mar 1;3(1):27. doi: 10.3390/tropicalmed3010027.
Abstract: Burkholderia pseudomallei is endemic in northern Australia, with cases of melioidosis most commonly occurring during the wet season in individuals with diabetes, hazardous alcohol use, and chronic kidney disease. Pneumonia is the most common presentation and the majority of patients are bacteraemic-however, infection may involve almost any organ, with the skin and soft tissues, genitourinary system, visceral organs, and bone and joints affected most commonly. Central nervous system involvement is rarer, but has a high attributable mortality. Increased awareness of the disease amongst healthcare providers, ready access to appropriate antibiotic therapy and high-quality intensive care services has resulted in a sharp decline in the case fatality rate over the last 20 years. Further improvement in clinical outcomes will require a greater understanding of the disease's pathophysiology, its optimal management, and more effective strategies for its prevention.
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Journal title: Tropical medicine and infectious disease
Volume: 3
Publication Date: 2018-03-01
Type: Journal Article
DOI: 10.3390/tropicalmed3010027
Orcid: 0000-0002-1423-3839
Appears in Collections:(a) NT Health Research Collection

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