NT Health Research and Publications Online
Welcome to NT Health Research and Publications Online, an open access digital repository that showcases the research projects and output of researchers working for the Northern Territory Department of Health (NT Health), while also collecting and preserving publications and multimedia produced in an official capacity, that represent the department. This service is maintained by NT Health Library ServicesRecent Additions
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Journal ArticlePublication Cryptococcosis in the Northern Territory.(1976-11-27)This report represents a review of cryptococcosis in the Northern Territory from 1957 to 1975. There were 26 cases over a 19-year period; 25 of these were in full-blooded Aborigines. The disease occurred throughout the rural areas of the Territory as isolated cases. There were 24 cases of cryptococcal meningitis and only two with solitary lung involvement. The overall mortality was 50%. In all five untreated cases the disease was fatal. There were eight deaths among the 20 patients receiving chemotherapy, a mortality of 40%. Lung resection was performed in six cases of localized pulmonary cryptococcosis. The outcome for these was excellent. - Some of the metrics are blocked by yourconsent settings
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Journal ArticlePublication Remote health: what are the problems and what can we do about them? Insights from Australia.(2025-05-03)This article analyses three broad questions: (i) How is 'remote' different from 'rural'?; (ii) How do these differences affect the provision of health care and health outcomes, positively and negatively?; and (iii) What is needed to address these issues and systematise solutions in order to deliver parity of health outcomes? - Some of the metrics are blocked by yourconsent settings
Journal ArticlePublication An Improved Rapid and Sensitive Long Amplicon Method for Nanopore-Based RSV Whole-Genome Sequencing.(2025-05-01)Whole-genome sequencing (WGS) provides critical insights into the respiratory syncytial virus (RSV) transmission and any emerging mutations that could impair the efficacy of monoclonal antibodies or vaccines that have been recently licenced for clinical use worldwide. However, the ability to sequence RSV genomes at large scale is limited by expensive and time-consuming sequencing methods. Oxford Nanopore Technology (ONT) offers significant improvements in next generation sequencing (NGS) both in turnaround time and cost, compared with other platforms for viral WGS.We have developed and modified an RSV long amplicon-based WGS protocol for the ONT platform using a one-step multiplex RT-PCR assay and the rapid barcoding kit. One hundred thirty-five RSV positive Australian clinical specimens (91 RSV-A and 44 RSV-B) sampled in 2023 with cycle threshold (Ct) values between 14 to 35 were tested in this study. This ONT workflow was compared with other recent RSV WGS amplification assays based on short amplicons.A PCR amplicon clean-up step prior to library preparation significantly improved WGS result for samples with poor amplicon generation, but it is not necessary or beneficial for ones that generated high concentrations of amplicons. Overall, a success rate of 85.9% was achieved for WGS. This method performed as well as the more complex short amplicon methods in terms of genome coverage and sequencing depth.The workflow described here was highly successful in generating RSV WGS on ONT platform and had improved turnaround times and excellent results with RSV clinical samples with Ct values up to 30.4 - Some of the metrics are blocked by yourconsent settings
Journal ArticlePublication Case of a Rare Paediatric Injury With Bone Erosion: Embedded Ring in an 8-Year-Old.(2025-04-29)No abstract available4
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Fact sheetPublication PS5 Standard for Pharmacy Based Immunisation Programs(Department of Health, 2021-04)PS5 Standard for Pharmacy Based Immunisation Programs62243 1253 - Some of the metrics are blocked by yourconsent settings
FormPublication Application to register radiation apparatus(Department of Health, 2020)Application for registering a radiation apparatus30173 2276 - Some of the metrics are blocked by yourconsent settings
FormPublication 29588 2136 - Some of the metrics are blocked by yourconsent settings
ReportPublication 23582 3449 - Some of the metrics are blocked by yourconsent settings
BulletinPublication 21677 74153