Murray, R

Mallal, S

Heath, C

French, M

2001-03

Reported here is a case of cerebral Mycobacterium avium complex infection that occurred in an HIV-infected patient, who had been treated for disseminated infection and had discontinued clarithromycin and ethambutol following a significant rise in his CD4+ T-cell count after starting highly active antiretroviral therapy. He responded well to excision of the lesion and reinstitution of multidrug therapy. Caution should be exercised when considering ceasing maintenance therapy for disseminated Mycobacterium avium complex infection in HIV-infected patients who demonstrate an apparently good immunologic response to highly active antiretroviral therapy, as this response may not necessarily restore protective immunity against all opportunistic pathogens.

Department of Microbiology, Royal Darwin Hospital, Casuarina, Northern Territory, Australia. ronanmurr@bigpond.com.

European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology 2001-03; 20(3): 199-201

0934-9723

https://pubmed.ncbi.nlm.nih.gov/11347672/?otool=iaurydwlib

https://hdl.handle.net/10137/6831

AIDS-Related Opportunistic Infections

Adult

Antiretroviral Therapy, Highly Active

Brain Diseases

CD4 Lymphocyte Count

Humans

Male

Mycobacterium avium-intracellulare Infection

Cerebral mycobacterium avium infection in an HIV-infected patient following immune reconstitution and cessation of therapy for disseminated mycobacterium avium complex infection.

Case Reports

Journal Article

Publication