Surprisingly low seroprevalence of Burkholderia pseudomallei in exposed healthy adults in the Darwin region of tropical Australia where melioidosis is highly endemic.

Author(s)
James GL
Delaney B
Ward L
Freeman, Kevin
Mayo MJ
Currie, Bart
Publication Date
2013-05-01
Abstract
In the Darwin region of Australia where melioidosis is highly endemic, only 11/354 (3%) healthy residents were seropositive by indirect hemagglutination assay, despite extensive exposure to Burkholderia pseudomallei. None developed melioidosis, but some described a prior self-limiting illness. This seropositivity rate is much lower than that seen in northeast Thailand, where melioidosis is similarly highly endemic, potentially reflecting important differences between these two locations in the epidemiology of melioidosis.
Affiliation
Emergency Department, Royal Darwin Hospital, Darwin, Northern Territory, Australia..
Citation
Clin Vaccine Immunol . 2013 May;20(5):759-60. doi: 10.1128/CVI.00021-13. Epub 2013 Mar 27.
Pubmed ID
https://pubmed.ncbi.nlm.nih.gov/23536689/?otool=iaurydwlib
Link
MESH subject
Adult
Antibodies, Bacterial
Australia
Burkholderia pseudomallei
Female
Hemagglutination Tests
Humans
Male
Melioidosis
Middle Aged
Seroepidemiologic Studies
Young Adult
Title
Surprisingly low seroprevalence of Burkholderia pseudomallei in exposed healthy adults in the Darwin region of tropical Australia where melioidosis is highly endemic.
Type of document
Journal Article
Entity Type
Publication

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