Patients presenting to Emergency Department (ED) with shock caused by infection (septic shock) as a part of
standard care receive resusdtation with intravenous fluids and/or vasopressors (medication to raise the blood
pressure). This study is a randomised, clinical trial of a restricted intravenous fluids and early vasopressor
strategy compared to a larger initial intravenous fluid volume and later vasopressors for patients with septic
shock. We hypothesise that a restricted fluids volume and early vasopressors approach, compared to a larger
initial fluid volume and later introduction of vasopressors approach to restore blood pressure, will increase the
number of days alive and out of hospital at day 90 in patients presenting to the ED with early septic shock. The
allocated fluid/vasopressor strategy will be followed for 6-24 hours.